In a 2002 report, the U.S. Geological Survey announced 95 new contaminants in American waterways. Among them, the problem of sulfonamides contaminants is particularly prominent. Sulfonamides are a class of synthetic antibacterial drugs, which have killing effects on most gram-negative bacteria and gram-positive bacteria, so they are widely used. Although these drugs and metabolic intermediates can be partially removed through adsorption, biological and abiotic degradation in the environment, these drugs are difficult to be completely degraded in the environment, and will eventually enter environmental water bodies, threatening the safety of aquatic organisms and even humans. Even low concentrations of antibiotics may also lead to the emergence of drug resistance, and sulfa drugs in the environment may cause the emergence of drug-resistant bacteria and bring about biological safety problems.
Fig. 1 The chemical structure of sulfa drugs
Sulfonamides can be used for prevention and treatment as veterinary drugs, and can also be added to feed as growth promoters. At the same time, sulfa drugs are commonly used therapeutic drugs for humans, mainly for the treatment of bacterial infections. It is estimated that they account for 16-21% of annual antibiotic usage. These compounds are excreted into the environment and become environmental contaminants that endanger biological health. In order to reduce pharmaceutical contaminants in the environment, ELISA testing is used to monitor the concentration and source of these drugs.
Creative Diagnostics has been committed to pharmaceuticals contaminants testing by ELISA. We provide ELISA kits products, customized ELISA kits services, ELISA testing services and ELISA development services related to the detection of sulfonamides contaminants. If you wish a lot of careful data, please be at liberty to contact us.