
Autophagy is a vital cellular self-protective mechanism in which cells degrade damaged or excess components and recycle them into energy and building blocks. This process plays a critical role in maintaining cellular homeostasis, stress responses, and the development of diseases such as neurodegeneration, cancer, and metabolic disorders. Accurately and efficiently measuring and modulating autophagy is essential for target validation and basic research.
Leveraging high-content imaging, flow cytometry, and lentiviral gene modulation techniques, Creative Diagnostics delivers a comprehensive suite of autophagy research solutions:
Our advanced platform integrates high-content imaging, flow cytometry, and real-time fluorescence and chemiluminescence assays to monitor autophagy dynamics at multiple levels. We design and produce lentiviral vectors for precise gene overexpression or knockdown, ensuring efficient transduction and stable expression. With exceptional high-throughput screening capabilities, we support large-scale small-molecule and genetic studies. Stringent use of internal controls, replicate testing, and multi-parameter validation guarantees data accuracy and reproducibility. We also offer customized protocols for different cell types, gene targets, and treatment conditions to meet your specific research needs.
Define research goals, autophagy markers, and cell line background
Select screening or detection methods and plan viral vector strategies
Transduce or infect cells, induce or inhibit autophagy, then perform imaging or flow cytometry assays
Quantify imaging data, process flow cytometry results, and conduct statistical analysis
Provide raw data, analysis charts, and interpretive recommendations
Partner with us for autophagy research services that deepen your understanding of autophagy regulation and accelerate target validation and drug discovery. We look forward to collaborating with you!