Comprehensive Dengue NS1 Antigen & IgG/IgM Antibody Panel

Digital illustration of Dengue virus

Dengue Fever is an acute infectious disease caused by the Dengue virus (DENV, comprising four distinct serotypes) and transmitted by mosquito vectors. In research focusing on DENV infection mechanisms and epidemiology, accurately capturing the precise phases of viral activity and host immune responses is absolutely critical.

Traditional virological and serological assays each have a distinct "blind spot": viral RNA loads typically decline to negative levels rapidly around day 5 post-infection, whereas host-specific IgM antibodies often do not turn positive until day 6 or later. Dengue NS1 (Non-Structural Protein 1) antigen testing perfectly bridges this critical "time window." Secreted abundantly into the bloodstream during the early stages of infection, the NS1 protein acts as an effective bridge between RNA and IgM testing. It is a core biomarker for identifying early acute viral exposure and building complete, unbroken infection kinetic models.

Our Services

We provide infectious disease research teams and biopharmaceutical companies with a one-stop, multi-target Dengue serology research solution. With a single assay, this comprehensive panel completely profiles the infection trajectory of your experimental models or epidemiological samples:

  • Dengue Virus NS1 Antigen Detection: Precise quantitative/qualitative analysis of NS1 protein levels in samples, providing direct biochemical evidence of viral activity during the acute phase (days 1–7 post-onset).
  • Dengue IgM Specific Antibody Detection: Evaluating the host's early, acute-phase immune response triggered by viral exposure.
  • Dengue IgG Specific Antibody Detection: Tracking the host's long-term immune memory status. Titer variations help researchers evaluate past infection history and assess the risk of secondary infections.

Sample Requirements

To ensure the absolute rigor and reproducibility of your research data, please strictly adhere to the following sample guidelines:

  • Preferred Sample Type: Serum.
  • Sample Volume: A volume of 1.5 mL is highly preferred; the absolute minimum acceptable volume for micro-experimental models is 0.6 mL.
  • Specimen Stability:
  • Room Temperature: Stable for 7 days.
  • Refrigerated (2-8°C): Stable for 14 days.
  • Frozen (-20°C or below): Stable for 30 days.

Our Advantages

  • Seamless Full-Cycle Coverage: By combining NS1 antigen with IgG/IgM antibodies, this panel effectively eliminates the false-negative risks associated with single-target testing at specific time points, achieving complete coverage from early viremia to long-term immunity.
  • Strict Research Quality Control: Utilizing internationally recognized, high-sensitivity immunoassay platforms, we establish rigorous inter- and intra-assay quality control baselines to ensure high specificity, even against backgrounds with cross-reactive serotypes.
  • High Sample Tolerance: Thanks to an optimized assay design, this panel boasts exceptional tolerance regarding sample storage conditions (stable for 7 days at room temperature), making it perfectly suited for complex environments like field epidemiological sampling and cross-regional cold-chain logistics.

At the forefront of research tackling global arboviral threats like Dengue, comprehensive and gap-free virological and immunological data is the foundation of scientific breakthroughs. Contact our expert team today to customize your Dengue comprehensive testing plan, and let our high-standard research data accelerate your R&D pipeline!

The service is for research only, not for clinical use.
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