Ultra-Deep Blood Proteome Analysis

Blood is the primary sample type in medical testing, and changes in protein levels serve as indispensable indicators for clinical diagnosis, holding significant research value for early disease detection and prognosis guidance. In recent years, with advancements in mass spectrometry technology, proteomic approaches for screening new blood biomarkers have become an increasingly important direction for both research and clinical translation. This provides a powerful tool for studying oncology, cardiovascular and cerebrovascular diseases, neurological disorders, immune system diseases, and reproductive development.

Our ultra-deep blood proteome analysis technology deeply mines low-abundance protein biomarkers in blood, overcoming the limitations of traditional detection methods and offering a fresh perspective for exploring disease mechanisms and precision medicine strategies.

Technical Principle

Traditional blood proteome analysis often uses strategies to remove high-abundance proteins. However, this process can non-specifically remove large quantities of low-abundance proteins, leading to the loss of critical protein information.

Our ultra-deep blood proteome analysis service employs an innovative low-abundance protein enrichment solution. This method selectively retains and enriches low-abundance proteins in blood while effectively removing the interference from high-abundance proteins, thereby significantly improving the detection capability for low-abundance proteins. This technology breaks through the bottlenecks of traditional methods, offering an ideal solution for the in-depth exploration of blood biomarkers.

Service Offerings

Our ultra-deep blood proteome analysis service provides:

• Comprehensive Protein Identification and Quantification: Achieves in-depth identification of proteins in blood samples, significantly improving protein detection rates.
• Specific Enrichment of Low-Abundance Proteins: Focuses on the low-abundance protein region that is difficult to detect with traditional methods.
• Customized Data Analysis: Includes differential expression analysis, functional enrichment analysis, protein-protein interaction network construction, and biomarker screening.
• Machine Learning-Assisted Biomarker Discovery: Utilizes advanced algorithms to screen for potential disease biomarkers.

Service Advantages

• Exceptional Detection Depth: Our technology elevates the depth of protein identification in blood samples to a new level, strongly supporting the discovery of novel protein biomarkers.
• Advanced Technology Platform: Combines innovative protein enrichment methods with high-precision mass spectrometry technology to ensure data accuracy and reliability. A strict quality control system guarantees stable and reliable data for large cohorts.
• Professional Analytical Capabilities: Leverages advanced machine learning algorithms for biomarker screening, combined with years of experience in large cohort projects. We have processed vast numbers of samples, leading the industry in data interpretation capabilities.
• Broad Application Scope: The technology is suitable for various body fluid samples containing highly abundant proteins, such as serum, plasma, lymph, cerebrospinal fluid, saliva, aqueous humor, tears, urine, and follicular fluid, providing solutions for diverse research needs.

Workflow

Sample Submission Guidelines

If you have project requirements or wish to learn more about technical details, please feel free to contact our professional technical team. We will provide personalized experimental design and technical consulting services.