Targeted Metabolomics Service
Targeted metabolomics is a technology that enables precise qualitative and quantitative analysis of specific groups of metabolites, using known standards as reference. Compared to untargeted metabolomics, it offers higher sensitivity, specificity, and accuracy, allowing it to uncover subtle changes within key metabolic pathways of living organisms. This technology has become an indispensable tool in fields such as disease biomarker discovery, drug mechanism research, nutritional health assessment, and precision medicine.
Our Services
We leverage advanced Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) platforms and core techniques like Selective/Multiple Reaction Monitoring (MRM/SRM) to establish a stable, sensitive, and high-throughput targeted metabolomics quantification system. By comparing sample data with standard reference data under identical analytical conditions, we provide you with precise absolute quantification results for your target metabolites.
Our comprehensive service portfolio includes:
Why Choose Us
We base our services on stable and reliable LC-MS/MS and MRM technology platforms, employing rigorously validated detection methods to ensure high reproducibility and accuracy of data. Our team possesses extensive project experience across various metabolite detection fields, enabling us to offer expert advice tailored to your specific research direction. We implement stringent quality control throughout the entire process—from sample preparation to final analysis—guaranteeing the authenticity and reliability of the results. In addition to providing precise quantitative data, we can also offer basic statistical analysis and biological interpretation support based on your needs. We are committed to supporting the smooth achievement of your research objectives through efficient and flexible service workflows.
Workflow
You communicate your specific research goals and sample information with us. We assist in finalizing the analyte list and developing the experimental plan.
You prepare and ship samples according to our guidelines. Our laboratory handles sample registration and pre-processing (e.g., extraction, derivatization).
Targeted metabolite analysis is performed using the LC-MS/MS platform to acquire raw mass spectrometry data.
We perform quantitative calculations and quality control assessment on the raw data, finally delivering a comprehensive analysis report containing metabolite concentration information to you.
Considerations
- Sample Preparation: Please strictly follow the collection, preservation, and shipping guidelines for different sample types (serum, plasma, tissue, cells, urine, etc.) to ensure metabolite stability.
- Information Provision: Providing as much detailed background information, grouping details, and key metabolic pathways of interest as possible will help us deliver a service more closely aligned with your needs.
- Standard Selection: For the analysis of special or rare metabolites, we recommend discussing the availability of reference standards with us in advance to facilitate smooth method establishment.
- In-Depth Data Mining: Integrating targeted metabolomics data with genomic, transcriptomic, or proteomic data for combined analysis is recommended for a more systematic interpretation of biological questions.
