Medical Targeted Lipidomics Solutions
Lipidomics is the discipline that systematically studies all lipids within an organism. By comprehensively analyzing the types, distribution, functions, and dynamic changes of lipids in physiological and pathological states, it reveals the critical role lipids play in life activities. As a vital branch of metabolomics, lipids are not only the core building blocks of cell membranes but also central regulators of energy metabolism, cellular signaling, and disease development.
In the era of precision medicine, dysregulation of lipid metabolism is closely linked to the onset and progression of many major diseases, such as metabolic syndrome, cardiovascular diseases, neurodegenerative disorders, and various cancers. Therefore, precise and systematic analysis of lipid molecules has become a forefront approach for uncovering disease mechanisms, discovering biomarkers, and exploring new drug targets.
We provide professional Medical Targeted Lipidomics analysis services for medical research. Leveraging advanced technological platforms and comprehensive in-house databases, we are committed to offering researchers and clinicians a comprehensive, accurate, and in-depth one-stop solution. We empower you to precisely capture the molecular trajectories of lipids within biological systems and extract key biological insights.
Our Services
Our core service is high-throughput targeted lipid detection and analysis based on Liquid Chromatography-Mass Spectrometry (LC-MS) technology. Our support covers the entire workflow from experimental design to biological interpretation:
- Comprehensive Lipid Coverage: Our targeted lipid database strictly adheres to international lipid classification standards, encompassing major categories such as Glycerolipids, Glycerophospholipids, Sphingolipids, Sterol Lipids, and Fatty Acyls. We enable absolute quantification of over 4,500 lipid molecules, including more than 3,100 glycerophospholipid species, providing you with unprecedented depth of coverage.
- In-Depth Bioinformatics Analysis: We deliver not just raw data, but a comprehensive analysis report with biological significance, including:
- Screening and statistical validation of differential lipid molecules.
- Analysis of abundance changes at both lipid subclass and individual molecular species levels.
- Fatty acyl chain length and unsaturation degree analysis.
- Lipid metabolic pathway enrichment analysis based on databases like KEGG.
Core Service Advantages
| Advantage Dimension | Detailed Description |
| More Comprehensive Database | Our in-house targeted lipid database covers eight major lipid classes and over 4,500 lipid molecules, with particular expertise in deep profiling of glycerophospholipids. |
| More Specific Substance Classification | Utilizes high-resolution MS/MS fragment information for precise identification and differentiation of lipid subclasses and molecular species, minimizing false positives. |
| More Accurate Quantitative Results | Employs multi-isotope internal standards and standard curves for absolute quantification, with stringent quality control throughout the process to ensure data accuracy and reproducibility. |
| Richer Analysis Content | Goes beyond conventional differential analysis to provide multi-level, one-stop bioinformatics interpretation—from molecular structure (chain length, saturation) to pathway function. |
| Expert Team Support | Our team, led by experienced PhD scientists, provides full-process professional consultation from project design and execution to data interpretation, supporting high-impact research outcomes. |
Workflow
Our expert team will engage in detailed communication with you to jointly determine the optimal detection and analysis strategy based on your research objectives and sample types.
Please perform sample collection according to the project plan. We provide detailed sampling guidelines covering common sample types such as serum/plasma, tissues, cells, and various body fluids. Clear instructions are given regarding minimum recommended amounts, pre-processing methods, and preservation/transport conditions (e.g., -80°C freezing, dry ice shipping) to ensure sample integrity.
Lipids are extracted using mature solvent systems like Methyl-tert-butyl ether (MTBE)/Methanol to ensure high recovery efficiency across lipids of different polarities.
Data acquisition is performed using high-performance Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) platforms under optimized chromatographic separation and Multiple Reaction Monitoring (MRM) modes.
We execute the full pipeline from raw data pre-processing and absolute quantification calculation to in-depth bioinformatics analysis, culminating in the delivery of a well-structured, thoroughly interpreted professional analysis report.
Application
Our services are widely applicable across numerous frontier fields in life sciences and medical research:
- Disease Mechanism & Biomarker Discovery: Investigate lipid metabolic remodeling in diseases like cardiovascular disease, type 2 diabetes, non-alcoholic fatty liver disease, Alzheimer's disease, and cancer. Screen for potential lipid biomarkers for early diagnosis and prognosis evaluation.
- Drug Discovery & Efficacy Assessment: Evaluate the impact of drug interventions on the body's overall lipid metabolic network, elucidate mechanisms of drug action, and identify lipid dynamics associated with pharmacological effects.
- Nutrition & Health Research: Explore the regulatory effects of different dietary components, functional nutrients, or probiotics on host lipid metabolism.
- Plant & Microorganism Research: Analyze changes in the plant lipidome under stress conditions or study lipid metabolic pathways in microorganisms.
We are confident that deep, accurate lipidomics data will be key to your next research breakthrough. Contact us today to request detailed information or to discuss your project. Let's explore the mysteries of the lipid world together.
