Human PSMA2 Ready-To-Use IHC Kit

Catalog No:

RTUI0348

Sample Type:

FFPE tissue

Storage:

Please store components at the temperatures indicated on the individual tubelabels.The kit is stable for 6 months from the date of receipt.

Size:

50T (including a control slide)

Notes:

The positive control slide provided in the kit allows you to be sure that the experimental set-up is working properly.
Do not allow slides to dry at any time during this procedure.
Please don't replace the matching reagents in this product with other manufacturers' products.
As DAB is a carcinogen, please take necessary precautions.
PBS (reagent 1) can be stored for one week at 4℃ after preparation; The antigen retrieval buffer (1×reagent 2) and the chromogenic agent (the mixture of reagents 7 and 8) should be prepared right before each assay.

Synonyms:

Lmpc3; MU; PSMA2; 20S Proteasome α2; HC3; Macropain subunit C3; MU antibody Multicatalytic endopeptidase complex subunit C3; PMSA2; Proteasome (prosome macropain) subunit alpha type 2; Proteasome alpha 2 subunit; Proteasome component C3; Proteasome subunit alpha type 2; Proteasome subunit alpha type-2; Proteasome subunit HC3; PSC2; PSC3; PSMA 2; psmA2; PSA2_HUMAN.

Introduction:

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composedof 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family,that is a 20S core alpha subunit.