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Mouse RUNX1/RUNX2/RUNX3 Ready-To-Use IHC Kit

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Product Overview

Catalog No:

RTUI0539

Product Name:

Mouse RUNX1/RUNX2/RUNX3 Ready-To-Use IHC Kit

Sample Type:

FFPE tissue

Product Properties

Storage:

Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.

Size:

50T (including a control slide)

Notes:

The positive control slide provided in the kit allows you to be sure that the experimental set-up is working properly.
Do not allow slides to dry at any time during this procedure.
Please don't replace the matching reagents in this product with other manufacturers' products.
As DAB is a carcinogen, please take necessary precautions.
PBS (reagent 1) can be stored for one week at 4℃ after preparation; The antigen retrieval buffer (1×reagent 2) and the chromogenic agent (the mixture of reagents 7 and 8) should be prepared right before each assay.

Target Info

Synonyms:

AML1; AML1-EVI-1; AML2; AML3; AMLCR1; Cbf; CBF-alpha-1; CBF-alpha-2; CBF2alpha; Cbfa-1; CBFA1; CBFA2; CBFA3; CCD; CCD1; CLCD; EVI-1; LS3; OSF-2; OSF2; PEA2aA; PEBP2A; Pebp2a1; Pebp2a2; PEBP2A3; PEBP2aA; PEBP2aB; PEBP2aC; PEBP2alpha; Pebpa2a; Pebpa2b; RUNX1; RUNX2; RUNX3.

Introduction:

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are welldocumented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for Clinical Use.